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If these measures are insufficient, bulk-forming laxatives such as ispaghula husk or osmotic laxatives like macrogol may be appropriate, following discussion with a GP or pharmacist

Brand Zepbound Indication Obstructive sleep apnea Population Adults with moderate-to-severe OSA who also have obesity

A healthcare provider will guide the narrowing process if discontinuation is necessary

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The Gut-Brain Axis and the Vagus Nerve The GLP-1 produced in the intestines after a meal also plays a role in suppressing eating, likely through different circuits than those GLP-1-expressing neurons found in the brain stem