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Women of reproductive potential should discuss contraception and pregnancy planning with their healthcare team before initiating tirzepatide therapy

It should be stored in a refrigerator until first use but then may be kept at room temperature for up to 56 days

Lancet Diabetes Endocrinol 8(5):392406 Husain M, Birkenfeld AL, Donsmark M, Dungan K, Eliaschewitz FG, Franco DR, Jeppesen OK, Lingvay I, Mosenzon O, Pedersen SD, Tack CJ, Thomsen M, Vilsbll T, Warren ML, Bain SC (2019) Oral semaglutide and cardiovascular outcomes in patients with type 2 diabetes

Patients with pre-existing conditionsincluding kidney disease, heart disease, history of ulcers, or those taking anticoagulantsshould proactively discuss NSAID use with their healthcare team before starting ibuprofen

They can determine the cause, adjust the dosage, or find an alternative drug that works better for you