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Therefore, finding effective and low-toxic active substances from traditional Chinese medicines for treating rheumatoid diseases, or developing more efficient and quality-controlled drugs based on them, is also an important development direction for treating RA at present and in the future

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For instance, randomized controlled trials investigating postbiotics alone or in combination, as well as the long-term efficacy of probiotic-drug synergistic regimens in real-world settings, necessitate further in-depth investigation

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