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Conclusions The prevalence of T2D in older adults will continue to increase in line with the rise in age-related factors, such as insulin resistance, deficient insulin secretion, and changes in body composition and loss of muscle mass

The CagriSema combination achieved over 20% weight loss in clinical trials - significantly more than either drug alone

In addition to acting as an agonist for GLP-1 and GIP receptors, it also targets the glucagon (GCG) receptor (7)

While bacterial pathogens are primary drivers, abomasal homeostasis is further challenged by a diverse array of non-bacterial agents

Author contributions All authors listed have made a substantial, direct, and intellectual contribution to the work and approved it for publication