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The peptide promotes M2 macrophage polarization, shifting the immune response from a pro-inflammatory to a pro-regenerative state

Further, a common genetic variant of GPX1 was found to be under transmitted from parents to children with autism spectrum disorder, suggesting a protective effect of a wild-type GPX1 (Ming et al., 2010)

The educt 4-chloro-17-methyl-5-androstane-3,17-diol is also not commercially available

Morel F, Rauch C, Petit E et al (2004) Gene and protein characterization of the human glutathione S-transferase kappa and evidence for a peroxisomal localization

"Structural analysis of human alpha-class glutathione transferase A1-1 in the apo-form and in complexes with ethacrynic acid and its glutathione conjugate"