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PMPs carry a cargo of bioactive lipids, oxidized phospholipids, and surface receptors that can prime neutrophils for an enhanced oxidative burst and NET formation

J Investig Dermatol 127(6):14031409 Li W, He X, Zhu J, Zhang H (2021) Qingre Huoxue Decoction, A Traditional Chinese Herbal Formulation, Impacts Angiogenesis in Psoriasis-Like Skin Through the HIF-1/Flt-1/VEGF Pathway Lin Y-K, Huang Z-R, Zhuo R-Z, Fang J-Y (2010) Combination of calcipotriol and methotrexate in nanostructured lipid carriers for topical delivery

GCase activity is correlated with increased neuroinflammation, -syn aggregation, and neurodegeneration [159,160,161]

Tirzepatide is FDA- and EMA-approved (Mounjaro/Zepbound)

Lundh B, Cavallin-Stahl E, Mercke