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The novelty of this review lies in its integrative approach, moving beyond a mere description of disparate pathways to synthesize a coherent framework that connects key metabolic nodessuch as the mammalian target of rapamycin (mTOR)-hypoxia-inducible factor 1-alpha (HIF-1)-glycolysis axis, AMP-activated protein kinase (AMPK)-FAO signalinginto a dynamic immunometabolic network ( Figure 1 )

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Improved blood circulation during training helps remove metabolic byproducts, while increased blood circulation at rest facilitates the delivery of nutrients to target muscles, promoting tissue recovery and reducing muscle soreness

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