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In contrast, women with preeclampsia are characterized by higher BMI, higher levels of blood lipid and lipid peroxides (24), which can be decomposed into more free radicals, thus damaging vascular endothelial cells, causing the decrease of prostacyclin (PGI2) by inhibiting PGI2 synthetase and activating thromboxin (TXA2) synthetase to produce TXA2 (25)

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This regimen normalized grafted kidney function and prolonged grafted kidney survival by two months by effectively treating AMR and reducing serum donor-specific antibody (DSA)[75]

The risks are higher because of unregulated use and unknown purity

T.CongiR.et al (2022)