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The pharmacology of the native IGF-1 system has been characterized in peer-reviewed studies published in the New England Journal of Medicine , Endocrine Reviews , and other top journals, and the IGF-1 LR3 analog has been characterized in the American Journal of Physiology Endocrinology and Metabolism and Drug Testing and Analysis
Since there are no FDA-approved versions of these peptides, compounding pharmacies could be the only pathway through which people could access these medications in the future, said Dresser, who has represented a number of compounding pharmacies
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A Mendelian randomization study in Frontiers in Endocrinology found that genetically predicted higher insulin resistance was associated with worse cognitive performance, with changes in brain cortical structure mediating part of the effect