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It is also being studied for: Primary generalized tonic-clonic seizures Major depressive disorder Bipolar depression Potential advantages Once-daily oral capsule No dose titration is required before reaching the target dose

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[16] Influenza syndrome was reported in 6% of postmenopausal women with operable breast cancer who received adjuvant tamoxifen therapy (n = 3094) in the ATAC trial

N Engl J Med 373(22):21172128