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Quantitative Structure-Activity Relationship (QSAR) Analysis QSAR modeling played a crucial role in understanding how structural modifications affect GLP-1 receptor agonism

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Disulfide bonds remain stable in the extracellular environment but are cleaved in the reductive intracellular milieu, characterized by elevated glutathione levels, leading to liposomal destabilization and subsequent drug release

doi:10.1093/toxsci/kfr112

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