& Ross, J
Efficacy of oral long-term N-acetylcysteine in chronic bronchopulmonary disease: a meta-analysis of published double-blind, placebo-controlled clinical trials
reviewed that succinic acid facilitates tumor development by providing an energy source and converting tumor-associated M2 macrophages, which suppress the anti-tumor immune response in ovarian cancer (79)
The undesirable pathway can further be nullified through methylation
In total, more than 10,000 qualified cells per group were collected, cells of each group were randomly clustered into 23 subclusters and annotated into 9 major cell types, namely, granulosa cells (GCs), fibroblasts, theca cells, endothelial cells (ECs), ovarian surface epithelial cells (OSECs), oocytes, myeloid cells, erythrocytes, T and natural killer (NK) cells, and myeloid cells, among which T and NK cells and myeloid cells are immune cells (Fig