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4 The American Society of Anesthesiologists (ASA) have recently issued guidance which advises patients taking GLP-1RA to withhold taking these medications prior to elective surgical procedures

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Baseline estimated renal function was normal (eGFR 90 mL/min/1.73m2) in 65.9%, mildly impaired (eGFR 60 to 90 mL/min/1.73m2) in 28.5% and moderately impaired (eGFR 30 to 60 mL/min/1.73m2) in 5.4% of the patients

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Clinical studies indicate that GLP-1 therapy added to metformin monotherapy typically lowers HbA1c by an additional 0.51.5% beyond metformin alone