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Silencing of nicotinamide nucleotide transhydrogenase impairs cellular redox homeostasis and energy metabolism in PC12 cells

6.2 Targeting metabolic pathways related to lactylation modification The metabolic changes in cancer cells, particularly increased glycolysis and lactate production, represent a unique vulnerability that can be exploited for therapeutic benefits

Hydrastis canadensis L

Around 5 10 5 cells were incubated in 5% (w/v) ZIL in DMEM after 2 h

These economic hurdles, combined with unequal access to quality healthcare, can result in delayed treatment, inadequate management of chronic illnesses, and worse health outcomes