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Participants may start with a low dose to monitor how their body responds and to manage potential side effects

Knowledge in this area is still sparse as structural modulation of the gut microbiome has only been reported at a relative low level of resolution (phylum/genus level) following treatment with agonists selective for the GLP-1 31,32,33,34 and GLP-2 25,35 receptors

Its Phase 3 data show double-digit weight-loss, deep HbA 1c cuts, and promising cardiometabolic markersall while regulators on two continents fast-track review

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