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Recent attention in the field of glucagon research has highlighted its potential for inducing weight loss in obese patients through mechanisms like lipolysis, thermogenesis, and enhanced energy metabolism [103]

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In psoriatic lesions, hyperactivated dendritic cells release cytokines such as TNF-, IL-12, and IL-23, which promote the differentiation of Th1 and Th17 cells (Chiricozzi et al

In a clinical setting, cotadutide improved postprandial glucose excursions and reduced body weight and hepatic fat in obese or overweight individuals with obesity or overweight people with type 2 diabetes 16,17 , showing the potential to deliver clinically meaningful effects