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However, chronic stimulation of these paracrine myofibroblast pathways in IBD raises theoretical safety concerns regarding stricturing, fibrosis risk, and the necessity for rigorous dysplasia surveillance, which remain critical hurdles for long-term clinical development

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Co-corresponding author and co-first author Fabio Hecht, PhD, and co-first author Marco Zocchi, PhD, led the study in the Harris lab in the Department of Biomedical Genetics

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