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Usually managed with medications and PCI (angioplasty/stenting) when needed

The people who deserve extra attention usually include: Patients with a known history of diabetic retinopathy Patients with diabetic macular edema Patients with recently worsening retinopathy Patients with poor baseline glucose control who may experience a large A1c drop Patients starting semaglutide while already under retina treatment Patients with multiple high-risk features such as kidney disease, hypertension, or long-standing diabetes In contrast, a patient with type 2 diabetes, no known retinopathy, and a recent normal dilated exam may still need routine follow-upbut often not the same level of concern as someone with active retinal disease

the constructs may be readily made using either recombinant manipulation and expression or using standard synthetic chemistry

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The injection trades a weekly needle for a more flexible schedule