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It binds with copper ions to support: Collagen and elastin production Tissue repair and wound healing Anti-inflammatory responses Cellular regeneration As levels decline with age, the skin becomes more prone to wrinkles, sagging, and uneven texture
Signs you may be underdosed Zero appetite changes after 2 or more weeks at a dose that should produce noticeable effects (typically 4mg and above)
The reasons for a link between vitamin B 12 deficiency and depression are not clear but may involve a shortage in S-adenosylmethionine (SAM)
Do not discontinue medication without medical guidance
Because of the key sex differences in the effect of ES [240,241,242,243] and nutrition [244] and general metabolisms [245] and disease prevalence and presentation [238, 239], it is key for future studies to consider both sexes when assessing efficacy of nutritional interventions in ES research and to include sex as a discovery variable
