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Ser-9 is conserved in epsilon, delta, theta, and unclassified GSTs and works to stabilize the GSH thiolate through a hydrogen bonding interaction [42, 73, 80, 83, 84, 86]

The timing and dose of antioxidant supplementation during chemotherapy require careful consideration to maximize treatment benefits while minimizing possible risks. Patients should talk to their doctors to make a plan that fits their treatment and health