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The early stage of this process is characterized by apoptosis, followed by cytoplasmic vacuolization, ER swelling and cell membrane rupture leading to cell necrosis [123, 124]

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Nutritional diarrhea induced by abrupt postpartum diet changes is associated with decreased total SCFAs and increased ammonia, indicating impaired microbial fermentation 89

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3.3 Short-chain fatty acids The structural integrity of the BBB is maintained by tightly joined brain endothelial cells, astrocytic end-feet, pericytes, and various transport proteins, which stringently regulate the penetration of substances from the blood into the brain tissue (103)

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