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For the longest time, people didn't know what he had until imaging studies suggested that areas in his brain might be affected by a metabolic disease, and Wilson disease was considered

NAD is generally considered safe in healthy invidivuals

It is important to consider potential variations in efficacy among subjects and potential differences in potency compared to injectable formulations

Lancet Neurol 17(1):8493 Bagheri H, Ghasemi F, Barreto GE, Rafiee R, Sathyapalan T, Sahebkar A (2020) Effects of curcumin on mitochondria in neurodegenerative diseases