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Numerous endogenous agonists activate the GLP-1R, including several forms of GLP-1, oxyntomodulin and glucagon, and multiple exogenous peptide agonists are approved, or in clinical development, for the treatment of type 2 diabetes and/or obesity 1, 2

As more clinical trials are conducted, researchers hope to provide definitive answers about semaglutides role in alcohol reduction

Examples of these include semaglutide (Ozempic, Wegovy, Rybelsus) and tirzepatide (Mounjaro, Zepbound)

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