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Additionally, using SIRT1 knockout mice and STAT3 knockout mouse models may provide more conclusive insights into GHKs mechanism of action
Anti-Aging and Collagen Stimulation Early histological studies demonstrated that GHK-Cu increases dermal collagen synthesis and glycosaminoglycan levels
In vitro, synovial fibroblasts exposed to GSH reduced IL-6 secretion, suggesting a retreat of synovial inflammation [6]
However, manufacturers marketing AOD-9604 as a supplement cannot make disease or therapeutic claims (e.g., "for weight loss" or "for treating obesity") without violating FDA regulations
Unpaired two-tailed Students t -tests were used for the comparisons between two groups
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