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Recommend excisional biopsy when the spot is on the palate or upper gum, has been present for an unknown duration, has any irregular features (asymmetry, ragged borders, mixed colour, recent change), or is in an aesthetically important area where the patient would like it removed

doi: 10.1016/j.jid.2016.02.813

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In addition to helping to create healthy red blood cells and replicate DNA in the nervous system, vitamin B-12 also helps contribute to the metabolic process

They are also transported by harvester ants, which is why milk thistle is often found near ant colonies