A retrospective analysis indicated GLP-1RA use was associated with reduced MS incidence (138), and a small study of dulaglutide in 13 patients demonstrated preserved endothelial function over 12 months (183)
Yang, Y., Gong, Y., Qu, S., Yin, G., & Liang, C
They're both classified as tissue-repair peptides, but the resemblance is more categorical than mechanistic
44 Although people with significant psychiatric illness are excluded from clinical trials, there has been no signal of increased psychiatric disorders in these studies but rather an improvement in quality of life measures with incretin therapy
Staining was performed at RT for 1h by using Mab 7F38 mouse anti-GLP-1R (DSHB, University of Iowa) 1.5g/ml, guinea pig anti Insulin (DAKO), rabbit anti-Calnexin (ENZO), rabbit anti-ZFPL1 (Atlas antibodies) and then with Alexa Fluor conjugated-secondary antibodies (Invitrogen)