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(PubMed) Lin J, Lee IM, Cook NR, et al

Any discomfort typically subsides quickly

Blind cage coding and automated video analysis (EthoVision, TopScan) are recommended Too low n : prior power analysis, n 8 minimum for rodent behavioural tests No positive control : without memantine, donepezil or scopolamine depending on the paradigm, impossible to judge if the model is functional No dose-response : a single tested dose is insufficient to conclude

While low B12 levels can signal a problem, they do not always reveal why absorption is impaired

Almost anyone with a confirmed B12 deficiency, absorption challenges, or wellness goals can consider home injections