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Breastfeeding women should also avoid berberine as it may be excreted in breast milk and could harm the infant

Diabetes Care 32 (9), 16491655

While this metabolic effect supports weight management, the primary driver of GLP-1mediated weight loss is reduced calorie intake rather than a substantial increase in energy expenditure

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Efficacy and safety of once-weekly semaglutide versus daily Canagliflozin as add-on to Metformin in patients with type 2 diabetes (SUSTAIN 8): a double-blind, phase 3b, randomised controlled trial