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If CrAT can generate acetyl-CoA for histone acetylation, we anticipated that the supplementation of acetylcarnitine to the culture media should boost histone acetylation and proliferation in lipid-depleted DKO cells, and this was indeed the case (Figure 6B, C)

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PMID: 38980576 | doi:10.1007/s10787-024-01499-8 Conato C et al

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