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Deletion of this gene in mice leads to the decrease in synaptic coverage by astrocytic leaflets, which translates into reduced densities of glutamatergic synapses

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This makes it an appealing option for patients who want to avoid the discomfort and downtime of surgery while still achieving significant fat loss

Hesperetin inhibits foam cell formation and promotes cholesterol efflux in THP-1-derived macrophages by activating LXR signal in an AMPK-dependent manner

Patients cannot absorb B12 orally, so IM injections are required indefinitely