Studies have shown that individuals carrying the TaqI polymorphism have significantly lower bone mineral density (BMD) compared to those without this variation, and this phenomenon is more pronounced in T2DM patients (17)
are obese defined as having a body mass index of 30 or higher and more than 22 million adults are severely obese, with a BMI of 40 or higher
Other side effects that can occur include: Excessive sweat production Rapid weight gain Pain when breathing Shortness of breath when lying down Anxiety Increased or irregular heart rate Numbness, tingling or muscular weakness Increased thirst Urinary frequency B12 injections can also cause allergy symptoms immediately after administration, like difficulty breathing, a swollen throat, mouth, or swelling of the mouth, tongue or face
Hong SW, Chun J, Kim J et al (2020) Efficacy and safety of ghrelin agonists in patients with diabetic gastroparesis: a systematic review and meta-analysis
Regarding the combination with injectable antidiabetic treatment, DPP-4 inhibitors can be used together with insulin