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Figure 3 illustrates the CNS signaling pathways associated with CFS pathogenesis

Metsera has a portfolio of therapeutic candidates and combinations with four programs in clinical development and several next-generation programs with IND-enabling studies ongoing, aimed at addressing key unmet needs via fewer injections while achieving improved efficacy and tolerability

13 One study showed that central obesity was strongly associated with BO, especially long-segment BO, in the White population but not in Hispanic or Black populations

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