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Their activation can increase the excitability of specific neuronal populations, thereby altering neural responses to food-related cues

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However, in addition to reports of increased risk of hemorrhage and heart failure with supplemental vitamin E in several randomized controlled studies (see Cardiovascular disease), a meta-analysis by Miller et al

While direct comparisons between ablation and surgical excision are limited, numerous observational studies indicate that ablation provides acceptable rates of local control and long-term survival, along with superior cosmetic outcomes

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