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Among the complementary mechanisms, immunomodulation stands out, where Artemisia derivatives enhance the host response by stimulating T cells and proinflammatory cytokines [38], as well as interference with macromolecule synthesis, such as the inhibition of DNA replication in Plasmodium [34, 35]

These enzymes include lipogenic enzymes (such as 6-phosphogluconate dehydrogenase (6PGD), glucose-6-phosphate dehydrogenase (G6PD), malic enzyme (ME), isocitrate dehydrogenase (ICDH), fatty acid synthase (FAS) and acetyl-CoA carboxylase (ACC)) and lipolytic enzymes (such as carnitine palmitoyltransferase 1 (CPT1), hormone-sensitive lipase (HSL) and adipose TAG lipase (ATGL)) ( Reference Elliott and Elliott 12 )

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L'tude a galement rvl une augmentation notable de la masse musculaire (+3.8 kg) et une rduction de la masse grasse (-1.8 kg) chez les personnes trs ges