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GLP-1 receptor agonists also have favourable effects on albuminuria and may slow eGFR decline , though the evidence for hard renal outcomes is less robust than for SGLT2 inhibitors

43 , e36 (2006)

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& Zhuang, J

Both boys and girls were included, but analyses were not sex-stratified ( Although often presented as a broadly beneficial polyphenol, resveratrol has also been repeatedly flagged as a potentially PAINS-susceptible molecule, owing to its redox activity, metal-chelating properties, and tendency to interfere with multiple assay formats in a non-specific manner as highlighted in the Nature commentary ( Weight of evidence: Overall evidence is Low : an add-on signal on hyperactivity without core-symptom change