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Nat Neurosci (2012) 15(12):170714

In a 16-week study of 103 patients treated with clozapine or olanzapine, the GLP-1 agonist liraglutide was associated with an average weight reduction of 11.7 lb versus placebo, as well as improvements in glucose tolerance, blood pressure, cholesterol, and visceral fat (Larsen JR et al, JAMA Psychiatry 2017;74(7):719728)

The matched cohort study of over 16,000 patients was published in JAMA Ophthalmology and found patients prescribed a semaglutide for the treatment of type 2 diabetes were 4 times more likely to develop the condition

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Efficacy: Mounjaro has shown strong a1c reduction and significant weight loss, often more effective than Ozempic and other appetite-reducing medications