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Work with the FDA and other agencies to update guidelines for lifestyle interventions in pediatric clinical trials that incorporate state-of-the-art approaches to quantifying, monitoring, and evaluating physical activity, adherence to diet, and accurate measurement of body composition beyond the current reliance on the body mass index (BMI), a suboptimal metric of overweight and obesity in adolescents
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Furthermore, in New Zealand obese mice, the GLP-1-estradiol conjugate protects against carbohydrate-induced hyperglycemia (250)
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doi: 10.1016/j.amjmed.2014.04.017 144 AzzizRCarminaEChenZDunaifALavenJSLegroRSet al
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