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Cavity I of the ghrelin receptor, which is relatively hydrophilic, contains four polar amino acids, including Asp99 2.60 and Arg102 2.63 , in addition to the salt bridge

The clinical trials of other glutamine antimetabolites, glutaminase inhibitors, glutamine uptake inhibitors have not been reported

Within neurons, oxidative stress may stem from mitochondrial dysfunction induced by the intracellular accumulation of hyperphosphorylated tau and A [84, 120]