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Ongoing totals begin at $348 and can reach $598 on the live price page, or $648 if the separate $499 Zepbound high-dose page applies

Can Chronic Stress Actually Cause Weight Gain

While that concern is completely normal, in many cases the actual risk is much lower than people assume

In practice, the long-acting GLP-1 RAs became preferred for general glycemic control due to convenience and greater A1c reduction, whereas short-acting ones like lixisenatide found a niche in combination products or for targeting post-meal glucose excursions (for instance, some use lixisenatide mainly to handle breakfast hyperglycemia)

Rare case-level evidence of paradoxical appetite increase and progressive weight gain during semaglutide therapy also suggests that behavioural and psychological factors may counteract expected anorexigenic effects in selected individuals (101)