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We further noted in the CY 2026 OPPS/ASC proposed rule that the two neuroplasty procedure codes that could be used with the Axoguard HA+ Nerve Protector TM (CPT codes 64718 and 64721) have previously been used with both categories C1763 and C1765 and that FDA has previously approved devices described by C1763 and C1765 and billed using CPT codes 64718 or 64721 for neuroplasty and/or transposition of the ulnar nerve at elbow or median nerve at carpal tunnel
235 Additionally, the oxidation of guanosine to 8-oxo-2-deoxyguanosine (8-oxodG) at CpG sites directly interferes with methylation
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