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Investigaciones con semaglutida, principalmente en poblaciones con obesidad (no especficamente con BED), han mostrado prdida de peso significativa, pero la extrapolacin directa de estos resultados a pacientes con trastorno de atracones requiere cautela

The peptide activates various immune pathways, and in some individuals, this activation may produce symptoms similar to fighting off an infection

However, in real-world practice, things rarely follow a perfect script

(66) further showed that the metabolic effects of IEC-specific TLR4 knockout could be reversed by treating mice with antibiotics, suggesting that TLR4 expression in IECs play a central role in protective host-microbe interactions

though interventions are in early stages, they represent a promising future direction