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If PPIs reduce symptoms, practitioners will generally say that they work

Deficiencies or imbalances can exacerbate symptoms such as pain, inflammation, bloating, and fatigue

This may cause moderate to severe discomfort

The FDA's formal evaluation process reviewed AOD-9604 against four statutory criteria: physicochemical characterization, safety, historical use in compounding, and available evidence of effectiveness

The identified classes in plants include DHARs, Elongation factor 1 gamma (EF1G), Lambda (GSTL), Phi (GSTF), Tau (GSTU), Tetrachlorohydroquinone dehalogenase (TCHQD), Theta (GSTT), and Zeta (GSTZ) (Mohsenzadeh et al., 2011)