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A meta-analysis looking at 1100 patients by Gurien found improved cannulation but no statistical difference in complication rate or arterial punctures between US-guided CVC insertion versus landmark technique [53]

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"It is incumbent upon the entire healthcare system to focus on innovative pricing, coverage, payment, and delivery solutions, with the goal of broadening access to effective obesity medications." Novo Nordisk and Lilly have launched direct-to-consumer sales channels to offer their obesity therapies for a fixed monthly fee, and have partnered with telehealth companies to broaden their reach

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