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Start gentle ROM (Week 1) gentle stretching (Weeks 2-4) progressive low-load strengthening (Weeks 2-4) Progress to resistance under PT supervision (Weeks 4-6) Follow structured protocol rather than self-directed progression Increase intensity/duration by no more than 10-15% per week What Should You Do If Symptoms Return After Activity

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BNIP3, a member of the pro-apoptotic protein family, is upregulated in response to hypoxic conditions and has been implicated in the induction of autophagic cell death (93)