*Correspondence: Su-Mei He, [email protected] Zhu, [email protected] Wei, [email protected] These authors have contributed equally to this work and share first authorship This article was submitted to Clinical Nutrition, a section of the journal Frontiers in Nutrition Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
A2: In cell and animal models, GHK-Cu has been shown to influence collagen and matrix turnover, recruit fibroblasts and endothelial cells, and support revascularization, making it a key tool for investigating skin repair and tissue-regeneration pathways
[3] [6] In the context of aging skin, oxidative damage and low-grade inflammation are plausible contributors to matrix degradation, so an agent that modulates both is mechanistically attractive
doi: 10.5853/jos.2019.00472 31 GuastiLGalliazzoSMolaroMViscontiEPennellaBGaudioGVet al
Jan 2021;70(1):1-16