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A slight modification of the eCATH-3 peptide (LLK-eCATH-3) realized by the substitution of only three amino acids caused a higher hydrophobicity and helical content resulting in a dramatic change of the antimicrobial activity

More research will be needed to decipher the molecular basis for this effect

2 Ascletiss ASC30 showed weight loss of up to 7.7% at week 13 in phase 2 trials

FDA requested healthcare professionals be notified sibutramine should not be used in patients with known cardiovascular disease

The guidelines suggest initiating lifestyle interventions in combination with metformin at the time of diagnosis ( Figure 3 )