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Physical dependence : Long-term use leads the body to rely on the substance to maintain baseline functioning, so abrupt cessation forces the body into a shock state, manifesting as withdrawal

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That could cause you to lose too much weight

This is a good thing because BAT is more metabolically active than WAT, so the more BAT you have, the more calories you'll burn specifically, as heat in a process called non-shivering thermogenesis

Across all trials, treatment pathways involving semaglutide are modelled to become dominant treatment strategies at approximately a 40% discount