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How Semaglutide Works: The GLP-1 Mechanism Explained To understand why semaglutide is so effective for weight loss, you need to understand the role of GLP-1 in your body

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The Phase 3 program, branded TRIUMPH, began reporting in 2026, and the early TRIUMPH-4 readout has been widely described in the trade literature as approaching 28.7% body weight reduction at the top dose over the trials primary endpoint window