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Diabetes 50 , 25302539 (2001)

Although the use of GLP-1 RAs prior to EGD or colonoscopy has resulted in poor outcomes in terms of poor visibility/preparation scores and the need for aborted/repeated procedures, their use prior to concurrent EGD and colonoscopy might not have the same detrimental effect

In particular, one study demonstrated that hippocampal GLP-1R deficient mice develop deficits in spatial and associative learning [57]

Interestingly, chronic LH GLP-1R knockdown resulted in increased nucleus accumbens (NAc) GLP-1R expression in male mice, which may be associated with compensation related to reward [97]

To get the best results from Semaglutide GLP-1, it is important to follow the dosing instructions provided by your healthcare provider