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Hoewel het zeer effectief is, kent het een specifiek bijwerkingenprofiel, waaronder maag-darmproblemen en dysesthesie, wat in studies leidde tot een iets hoger percentage stopzettingen van de behandeling

LC-GFP or LC-SYNCRIP plasmids were transfected into cells using Lipofectamine 3000 (L3000015, Thermo Fisher Scientific, USA) according to the manufacturer's instructions to generate control or SYNCRIP-deficient (KO) cells

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Stewart T, Rochon J, Lenfestey R, et al